Clinical-Trial Matching

Match patients to trial criteria from the record and surface candidates for clinician review.

What It Does

The agent reads the record against trial criteria, surfaces likely matches with the reasons, and routes them to a clinician to confirm.Without it: Matching patients to trials by hand is slow, so eligible patients are missed.

  • Reads pathology and molecular reports, not only problem-list diagnoses
  • Splits criteria into met, failed, and unanswerable from the record as it stands
  • Names the single exclusion that rules out a near miss, so it is not re-reviewed
  • Re-runs existing patients when a protocol amendment changes a criterion

Illustrative example

Protocol NCT-8841 opens for EGFR-mutant lung cancer with no prior systemic therapy. The agent reads molecular pathology across the thoracic clinic and returns each candidate with the mutation report cited, plus the near misses labelled with the single exclusion that ruled each one out, prior platinum therapy on some and a creatinine below threshold on another. The study coordinator takes the list to the treating clinicians, who decide whom to approach.

Reads

Trial registry

Open protocols, criteria

EHR

History, prior therapy

Pathology and labs

Mutation reports, lab values

Trial management

Enrollment, protocol amendments

Runs

Clinical-trial matching

Suggest

Starts when

A trial opens for enrollment, or a new patient is seen

How far it goes

it proposes, and a person approves before anything commits

Produces

Criteria matching

Split met, failed, unanswerable

Reasoned candidates

Listed with reports cited

Clinician confirmation

Pending, no patient approached

Clinical-trial matching. Reads Trial registry, Open protocols, criteria; EHR, History, prior therapy; Pathology and labs, Mutation reports, lab values; Trial management, Enrollment, protocol amendments. Suggest autonomy: it proposes, and a person approves before anything commits. Produces Criteria matching Split met, failed, unanswerable; Reasoned candidates Listed with reports cited; Clinician confirmation Pending, no patient approached.

Give Us One Stuck Pilot.

We'll have it in governed production before your next board meeting.